A subcortico-cortical cholinergic system is affected in Parkinson's disease
Identifieur interne : 000327 ( France/Analysis ); précédent : 000326; suivant : 000328A subcortico-cortical cholinergic system is affected in Parkinson's disease
Auteurs : Bruno Dunois ; Merle Ruberg ; France Javoy-Agid ; Alain Ploska ; Yves Agid [France]Source :
- Brain Research [ 0006-8993 ] ; 1983.
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Abstract
CAT activity was decreased in the frontal cortex and the substantia innominata of parkinsonians subjects, post-mortem. The decrease was greater in the frontal cortex of parkinsonians with dimentia. The density of muscarinic cholinergic receptors increased in the cortex. This increase was inversely correlated with tremor. The effectsof these parameters of both neuronal degeneration and anticholinergic therapy are discussed.
Url:
DOI: 10.1016/0006-8993(83)90096-3
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The decrease was greater in the frontal cortex of parkinsonians with dimentia. The density of muscarinic cholinergic receptors increased in the cortex. This increase was inversely correlated with tremor. The effectsof these parameters of both neuronal degeneration and anticholinergic therapy are discussed.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement><orgName><li>Hôpital de la Salpêtrière</li></orgName></list><tree><noCountry><name sortKey="Dunois, Bruno" sort="Dunois, Bruno" uniqKey="Dunois B" first="Bruno" last="Dunois">Bruno Dunois</name><name sortKey="Javoy Agid, France" sort="Javoy Agid, France" uniqKey="Javoy Agid F" first="France" last="Javoy-Agid">France Javoy-Agid</name><name sortKey="Ploska, Alain" sort="Ploska, Alain" uniqKey="Ploska A" first="Alain" last="Ploska">Alain Ploska</name><name sortKey="Ruberg, Merle" sort="Ruberg, Merle" uniqKey="Ruberg M" first="Merle" last="Ruberg">Merle Ruberg</name></noCountry><country name="France"><region name="Île-de-France"><name sortKey="Agid, Yves" sort="Agid, Yves" uniqKey="Agid Y" first="Yves" last="Agid">Yves Agid</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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